TECHNOLOGY LICENSING OPPORTUNITY: Bacterial Lipid Nanodiscs Platform
Special Notice from Department of Energy.
Data as of Oct 24, 2026. Sources: SAM.gov and Grants.gov. Snapshot govcon-directory-20261024T104923Z-2151694.
This product uses the Grants.gov API but is not endorsed or certified by the U.S. Department of Health and Human Services. Counts and totals are computed by DSE from public SAM.gov and Grants.gov notices. Text from Grants.gov may be shortened or have contact details removed. The original notice on Grants.gov is the authoritative version.
Closing in 53 days
Notice details
- Agency
- Department of Energy
- Sub-tier agency
- ENERGY, DEPARTMENT OF
- Notice type
- Special Notice
- Solicitation number
- S-191192
- Product/service code
- AJ11
- Place of performance
- Los Alamos, New Mexico
- Posted
- Jun 16, 2026
- Response deadline
- Dec 16, 2026
- Source
- SAM.gov
Description
The Bacterial Lipid Nanodiscs Platform developed by Los Alamos National Laboratory provides a new way to study entire bacterial membranes in a controlled, nanoscale format derived directly from native lipid extracts. Researchers gain access to membrane components that typically remain difficult to isolate, stabilize or analyze, enabling more accurate evaluation of immunogenic lipids and membrane?associated targets. The platform offers a safer alternative to handling live high?risk pathogens while preserving the biological context that drives meaningful insights for vaccine design and antimicrobial discovery such as therapeutic antibodies to conserved lipids on bacterial membranes. How it Works The Bacterial Lipid Nanodiscs Platform creates uniform nanoscale discs from total lipid extracts harvested from bacterial membranes. Membrane scaffold protein MSP1D1 encases the lipid mixture and forms a stable disc roughly 10 nanometers wide. The resulting particles retain the full complement of native bacterial lipids, arranged in a membrane?like environment that supports realistic biological interactions without requiring synthetic lipids or live cells. Technical Description The method adapts established nanodisc assembly techniques to incorporate entire bacterial lipid extracts rather than defined synthetic lipid mixtures. Total lipids from a pathogen are solubilized, combined with MSP1D1 and dialyzed under controlled conditions to allow the scaffold protein to form a discoidal
Summarized from the official notice. The description is shortened; read the full text on the official notice.
Official notice
Requirements and amendments are controlled by the official notice.
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See DSE GovCon plans →Prior awards (USAspending)
Department of Energy obligated $327,577,822 under NAICS 541715 on awards whose period of performance started in the last 12 months.
Source: USAspending.gov, U.S. Department of Treasury, Bureau of the Fiscal Service, https://www.usaspending.gov. Accessed Oct 24, 2026. Award totals are computed by DSE from USAspending.gov award data.
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Set up free alerts →Frequently asked questions
When is the response deadline?
The published deadline is Dec 16, 2026. That is 53 days after the data date.
What NAICS code applies?
NAICS 541715, Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).
Which agency issued this notice?
Department of Energy.
Where is the official notice?
The link under Official notice opens the source listing.